Progression of COVID-19 under the highly restrictive measures imposed in Argentina

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Jose-Luis Sagripanti
US Food and Drug Administration and US Department of Defense (retired), Annapolis, MD, United States.

Daniel R. Aquilano
Laboratorio de Análisis Bioquímicos Dr. Daniel R. Aquilano, La Plata, Buenos Aires, Argentina.


The variety and extent of non-pharmaceutical measures implemented by the government to control COVID-19 in Argentina were exceptional, making this country the best example to analyze the evolution of COVID-19 under the most stringent and longer-lasting restrictive policies- which included 119 days of strict nation-wide lock-down, 304 days of less restrictive lock-downs, and 35 days of curfews. Two of the three peaks of infection correlated with the germicidal solar flux received in Argentina, suggesting a seasonal component and a role for the virus persisting in the environment.

A massive public gathering crowding the presidential square in Buenos Aires, during which nearly half of those present were without face masks, did not alter the infection curve in that city. Comparative epidemiological data (standardized per million inhabitants) shows that COVID-19 in Uruguay, a neighboring country whose capital is at a similar latitude than Buenos Aires and who did not mandate lock-downs or curfews, progressed much slower (until vaccination started) than in Argentina.

The number of yearly deaths caused by respiratory diseases and influenza in Argentina before the pandemic was similar to the total number of deaths attributed to COVID-19 cumulated on April 25, 2021, more than a year after the pandemic started. The failure to detect any benefit on ameliorating COVID-19 by the long and strict nation-wide lock-downs in Argentina should raise world-wide concerns about mandating costly and ineffective restrictive measures during ongoing or future pandemics.



Walker PGT, Whittaker C, Watson O, et al. Imperial College of London's Report 12. The global impact of COVID-19 and strategies for mitigation and suppression. 2020 Mar. Accessed: 2020 May 1. Available from:

Flaxman S, Mishra S, Gandy A, et al. Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe. Nature 2020;584:257-62. DOI:

Sagripanti J-L. Prestige does not bring truth. How apocalyptic predictions may have altered the natural evolution of COVID-19. CBRNe WORLD 2020 (Summer/August issue) 40-43.

Cheng C, Barceló J, Hartnett A, et al. COVID-19 Government Response Event Dataset (CoronaNet v.1.0). Nat Hum Behav 2020;4:756-68. DOI:

Sandford A. Coronavirus: Half of humanity now on lockdown as 90 countries call for confinement. [Internet] Euronews 2020. Accessed: 2020 May 20. Available from:

Borracci RA, Giglio ND. Forecasting the effect of social distancing on COVID-19 autumn-winter outbreak in the metropolitan area of Buenos Aires. Medicina (B Aires) 2020;80:s7-15.

Larrosa JMC. SARS-CoV-2 in Argentina: Lockdown, mobility, and contagion. J Med Virol 2021;93:2252-61. DOI:

Dunfordv D, Dale B, Stylianou N, et al. Coronavirus: The world in lockdown in maps and charts. British Broadcasting Service. 2020. Accessed: 2020 Apr 7. Available from:

Argentine Government Bulletin. [Decreto de Necesidad y Urgencia, DNU # 297/2020). Aislamiento Social y Preventivo].[In Spanish]. Accessed: 2020 Mar 19. Available from:

Ministry of Health of Argentina. [Sala de situacion, Comunicados diarios (COVID-19 daily reports)].[In Spanish]. March 3rd 2020 to May 31st 2021. Accessed: 2020 Mar 3. Available from:

Ministry of Health of Argentina. Estadisticas Vitales. Informacion Basica (Vital Statistics. Basic information)].[In Spanish]. Serie 5 Num 62. 2018. Available from:

Ministry of Public Health of Uruguay. 2020-2021. [Informe de situación sobre el coronavirus COVID-19 en Uruguay (Report on the Situation about COVID-19)].[In Spanish]. Available from:

John's Hopkins' Center for System Sciences and Engineering [Internet] Coronavirus Statistics. Stats real time. Accessed: 2020 May 7 to Dec 14. Available from:

Sagripanti J-L, Lytle CD. Estimated inactivation of coronaviruses by solar radiation with special reference to COVID-19. Photochem Photobiol 2020;96:731-7. DOI:

Blanco D. [Todo resfrío es coronavirus hasta que se demuestre lo contrario? Expertos criticaron la declaración de Carla Vizzotti. (Every cold is coronavirus unless otherwise demonstrated. Experts criticized Carla Vizzotti’s statements)].[In Spanish]. [Internet]. Accessed: 2020 Jul 9. Available from:

Vizzotti C. [El Ministerio de Salud recomendó evitar “hablar fuerte, cantar o reírse” sin tapabocas en lugares cerrados (The Ministry of Health recommended not to speak louder, sing or laugh in closed rooms)].[In Spanish]. Daily reports from de Ministry of Health. Live broadcast from the Pink House. Accessed: 2020 Aug 27. Available from:

Gonzalez Garcia G. Argentina’s Minister of Health [Internet]. Recommendations for safe sex [Text in spanish] [Cited 2020 Apr 16] Available from:

Argentine Government Bulletin. [Decreto de Necesidad y Urgencia DNU #605/2020. Distanciamiento Social Preventivo Obligatorio (Decree of Necessity and Urgency DNU #605/2020. Preventive and Mandatory Social distancing)].[In Spanish]. Accessed: 2020 Jul 18. Available from:

Argentine Government Bulletin. [Duelo Nacional por la muerte de Diego Maradona. Decreto 936/2020 (National mourning for the death of Diego Maradona. Decree 936/2020)].[In Spanish]. Accessed: 2020 Nov 25. Available from:

Argentine Government Bulletin. [Plan estratégico para la vacunación contra Covid-19 en la República Argentina. Boletin Oficial de Gobierno. Resolución 2883/2020 (Strategic plan for vaccination against Covid-19 in the Argentine Republic)].[In Spanish]. Resolution 2883/2020. Accessed: 2020 Dec 29. Available from:

Klempert Izaguirre R. [“Antes del cierre”, casi 2 millones de argentinos viajaron en Semana (Santa Easter Holiday travel 2 million travelers and reason for government restrictions)].[In Spanish]. Hoteltur 2021 [Internet]. Accessed: 2021 Apr 4. Available from:

Argentine Government Bulletin. [Medidas Generales de Prevención. DNU # 287/2021 (General Prevention Measures. DNU # 287/2021)].[In Spanish]. Accessed: 2021 Apr 30. Available from:

Frederic S. [Tras las denuncias, la Ciudad acusó al Gobierno de “politizar” el velorio y Frederic salió al cruce (The Government of Buenos Aires City blamed the National Government of politicizing the wake of Maradona)].[In Spanish]. Todo Noticias [Internet]. Accessed: 2020 Nov 28. Available from:

Bourdet G. [El mapa del COVID-19 en CABA (The map of COVID en Buenos Aires City)].[In Spanish]. Diario La Nación [Internet]. Accessed: 2021 Jun 13. Available from:

Country Reports [Internet]. Argentina Demographics. 2021. Accessed: 2021 Aug 20. Available from:

Country Reports [Internet]. Uruguay Demographics. 2021. Accessed: 2021 Aug 20.Available from: DOI:

Statistics Times [Internet]. GDP per capita of Argentina. Current World Bank figures. 2021. Accessed: 2021 Jan 01. Available from:

Sagripanti J-L. Seasonality and progression of COVID-19 among countries with or without lock-downs. Open J Epidemiol 2021;11:303-25. DOI:

Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: Estimation and application. Ann Intern Med 2020;172:577-82. DOI:

Chaudhry R, Dranitsaris G, Mubashir T, et al. A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomes. eClin Med 2020;25:100464. DOI:

Wieland T. A phenomenological approach to assessing the effectiveness of COVID-19 related nonpharmaceutical interventions in Germany. Saf Sci 2020;131:104924. DOI:

Broadbent A, Combrink H, Smart B. COVID-19 in South Africa. Glob Epidemiol 2020;2:100034. DOI:

Kuhbandner C, Homburg S. Commentary: Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe. Front Med 2020;7:761. DOI:

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