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Diabetic peripheral neuropathy and its determinants among patients attending a tertiary health care centre in Mangalore, India

Monisha D’Souza, Vaman Kulkarni, Unnikrishnan Bhaskaran, Humam Ahmed, Hegde Naimish, Anjali Prakash, Tabreez S, Bhanu Dahiya, Rekha Thapar, Prasanna Mithra, Nithin Kumar, Ramesh Holla, Darshan BB, Avinash Kumar
  • Monisha D’Souza
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Vaman Kulkarni
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India | drkulkarni.vaman@gmail.com
  • Unnikrishnan Bhaskaran
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Humam Ahmed
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Hegde Naimish
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Anjali Prakash
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Tabreez S
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Bhanu Dahiya
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Rekha Thapar
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Prasanna Mithra
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Nithin Kumar
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Ramesh Holla
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Darshan BB
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India
  • Avinash Kumar
    Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India

Abstract

Background. The burden of diabetes mellitus (DM) is on the rise especially in developing countries like India. Due to its chronic nature DM tends to cause many debilitating complications and diabetic peripheral neuropathy (DPN) is one of them. The aim of this study is to determine the prevalence of DPN among patients attending a tertiary care hospital and to identify the determinants associated with it.
Design and methods. A cross sectional study was conducted in Government Wenlock Hospital, Mangalore (India), during January-February 2014. A total of 208 patients with >5 year duration of DM were asked to respond to the patient history version of Michigan Neuropathy Screening Instrument (MNSI) and examinations were conducted after obtaining consent from them. The statistical analysis was done in terms of descriptive statistics and association between variables was tested using logistic regression test.
Results. The prevalence of DPN using the MNSI history version and MNSI examination were found to be 18.3% and 32.2% respectively. The major determinants associated with DPN were found to be male gender (OR: 2.7, CI: 1.4-5.1, P=0.001), smoking (OR: 5.8, CI: 1.9-17.3, P=0.001) and age >40 years (OR: 2.7, CI: 1.2-5.8, P=0.011).
Conclusions. The burden of undetected DPN was found to be higher among diabetics, with an especially higher prevalence among males, smokers and those with long standing diabetes mellitus. Interventions in the form of early detection through routine screening, smoking cessation and regular follow up examinations would go a long way in reducing the burden of disability among diabetics and improve their quality of life significantly.

Keywords

Diabetic neuropathies; Michigan Neuropathy Screening Instrument; prevalence; developing countries

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Submitted: 2014-11-13 12:35:26
Published: 2015-07-30 14:44:23
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Copyright (c) 2015 Monisha D’Souza, Vaman Kulkarni, Unnikrishnan Bhaskaran, Humam Ahmed, Hegde Naimish, Anjali Prakash, Tabreez S, Bhanu Dahiya, Rekha Thapar, Prasanna Mithra, Nithin Kumar, Ramesh Holla, Darshan BB, Avinash Kumar

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